A hose including at least one permeation resistant layer, an elastomeric layer overlaying each at least one permeation resisting layer, at least one reinforcement layer overlaying an elastomeric layer, and a cover layer overlaying the at least one reinforcement layer, wherein the at least one permeation resistant layer includes a plurality of sublayers of at least two different thermoplastics wherein the sublayers have a thickness of less than 2500 nanometers.