A protocol generator and presenter device provides stimuli to a subject to allow analysis of the effectiveness of marketing and entertainment materials. A protocol generator generates presentation parameters such as length of presentation, number of repetitions, number of physiological baselines, etc. The presenter device uses the presentation parameters to elicit responses from a subject that are then measured and analyzed using multiple neurophysiological modalities. Feedback is provided to the protocol generator and presenter device to dynamically update presentation parameters.

 
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