The disclosure relates generally to methods and apparatus for spectral
calibration of a spectroscopic system which includes a fiber array
spectral translator. One embodiment relates to a method for obtaining a
first image of a known substance using a photon detector and a fiber
array spectral translator having plural fibers, wherein the first image
comprises at least one pixel; providing a second image of the substance
wherein the second image comprises at least one pixel; comparing the
first image with the second image; and adjusting at least one pixel of
the first image based on the comparison of images to thereby obtain an
adjusted image.