A radio frequency (RF) radiation-protective enclosure for a cellular phone is disclosed. The RF radiation-protective enclosure includes a substrate and a reflection layer. The substrate includes an inner surface. The reflection layer is formed on the inner surface of the substrate. The surface of the reflection layer is formed with micro-protrusions. The micro-protrusions are configured for diffusely reflecting RF radiation emitted by the cellular phone, thus reducing reflected RF radiation from interfering with RF circuits of the cellular phone.