Analysis methods are provided that include generating a sample data set
using a sample, the sample data set comprising first and second data
sets, wherein each of the first and second data sets comprises at least
one of an analytical parameter and a sample characteristic acquired using
the analytical parameter; and using the first and the second data sets,
identifying the sample. Instruments including an ionization source
configured to apply different ionization energies to a sample to provide
different sample characteristics, and processing circuitry configured to
process the different sample characteristics to identify the sample are
provided.