A biomimetic biosynthetic nerve implant (BNI) casting device includes a matrix casting tube; a matrix casting tube protective shield comprising a male coupling portion joinable to a female coupling portion, wherein the joined portions encase the matrix casting tube; microchannel forming fibers; a fixing point for holding one end of the microchannel forming fibers; loading fiber guideholes for placement of the microchannel forming fibers; one or more ports for injection of matrix material into the casting tube; and a cell suspension loading well in fluid communication with the matrix casting tube when the device is fully assembled such that removing the fibers from the formed implant can draw fluid containing cells and/or other agents into the microchannels.

 
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