A method for stimulating angiogenesis is provided that includes the use of
an electrical output channel adapted to deliver a sub-threshold voltage,
a lead that includes a proximal end adapted to be electrically connected
to the electrical output channel and a distal end adapted to be placed in
the blood conduit where the distal end of the lead is adapted to deliver
a treatment agent that stimulates therapeutic angiogenesis, and at least
one electrode on the distal end of the first lead.