A system and method for maintaining an air inflation mattress configuration sufficient for patient support and comfort. Infrared illumination levels are measured within individual or groups of inflated mattress chambers. A staggered approach to illumination monitoring of chambers or sections to eliminate crosstalk between the infrared sensors is carried out. Distributed microprocessor controllers established in a network configuration utilizing controller network protocols reduces the wiring and connections necessary for the assembled system. Various mattress cushion construction techniques, such as sewing and or RF welding methods, are used for the creation of individual chambers utilizing specific types of IR translucent, transparent or reflective materials. The construction of the cushions and bladders in the system includes the use of various types of fabrics with low to high air loss qualities as required. The overall mattress assembly, including the control systems and the methodologies associated with such control systems, provide a unique approach to the maintenance of a consistently comfortable patient support surface. The use of a handheld unit for both programming the system and downloading information about the operation of the system is also anticipated. The specific cushion construction designs associated with the head, body, and foot cushion components of the mattress are tailored to operate specifically with the control capabilities (sensors and air flow regulators) of the invention.