The present invention relates to the use of standardized extract of Tinospora cordifolia as an immunoadjuvant in the treatment of renal disorders such as nephrotic syndrome and chronic recurrent urinary tract infections, both complicated and uncomplicated. The present invention also relates to pharmaceutical compositions comprising the standardized extract of Tinospora cordifolia. The present invention further relates to a method of treatment of renal disorders such as recurrent urinary tract infection particularly occurring due to relapsing E. coli, Klebsiella and other gram negative infections and to a method of treatment of nephrotic syndrome using standardized extract of Tinospora cordifolia as an immunoadjuvant in conjunction with conventional therapy.