Methods and systems for tone hopping are provided. In one embodiment, a method for an orthogonal frequency division multiplexing (OFDM) multipoint-to-point communications system comprises: establishing communication between a first remote unit of a plurality of remote units and a host unit, the plurality of remote units communicatively coupled to the host unit in a multipoint-to-point configuration; transmitting up to a plurality of tones from the first remote unit modulated with upstream information using OFDM; adjusting at least one characteristic of the up to a plurality of tones such that when any tones are transmitted from the first remote unit and at least one other remote unit of the plurality of remote units, the orthogonality of the tones received at the host unit is improved; and dynamically switching modulation between tones of the up to a plurality of tones based on an error-rate history of at least one of the tones.