The present invention relates to retroviral constructs that encode novel
monoclonal antibodies, novel fusion proteins, and chimeric monoclonal
antibodies and to methods of using and producing the same. In particular,
the present invention relates to methods of producing a fusion protein
comprising a microorganism targeting molecule (e.g., immunoglobulin or
innate immune system receptor molecule) and a biocide (e.g., bactericidal
enzymes) in transgenic animals (e.g., bovines) and in cell cultures. The
present invention also relates to therapeutic and prophylactic methods of
using a fusion protein comprising a microorganism targeting molecule and
a biocide in health care (e.g., human and veterinary), agriculture (e.g.,
animal and plant production), and food processing (e.g., beef carcass
processing). The present invention also relates to methods of using a
fusion protein comprising a microorganism targeting molecule and a
biocide in various diagnostic applications in number of diverse fields
such as agriculture, medicine, and national defense.