A connector system is provided for use in priming a fluid circuit. The
system includes a first connector and a second connector. The first
connector is configured to couple with one end of a conduit. The first
connector has a gas permeable membrane, a main lumen extending from the
gas permeable membrane, and a second lumen. The second lumen has a first
end configured to couple with a fluid source and a second end in fluid
communication with the main lumen. The second connector is configured to
couple with an end of a cannula. The second connector has an end
configured to be inserted through the gas permeable membrane into the
first connector, whereby fluid communication can be established between
the main lumen of the first connector and the cannula lumen.