A toothbrush includes a handle that is sized and configured for grasping, and a head that is provided with bristles. The head may be removed from the handle and replaced. Toothpaste may be contained in the head and forced into the bristles. The handle and a number of heads may be provided in a kit. Each head is provided in a separate sealed housing that allows the head to be attached to the handle without requiring a person assembling the toothbrush to remove the head from the packaging or touch the head.