The present invention provides a novel compound having an excellent JNK inhibitory effect. That is, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. ##STR00001## Wherein R.sup.1 designates --(CO).sub.h--(NR.sup.a).sub.j--(CR.sup.b.dbd.CR.sup.c).sub.k--Ar (wherein R.sup.a, R.sup.b and R.sup.c each independently designate a hydrogen atom, a halogen atom, hydroxyl group, an optionally substituted C.sub.1-6 alkyl group or the like; Cy designates a 5- or 6-membered heteroaryl; and V each independently designate the formula -L-X--Y (wherein L designates a single bond, an optionally substituted C.sub.1-6 alkylene group or the like; X designates a single bond or the formula -A- (wherein A designates NR.sup.2, O, CO, S, SO or SO.sub.2) and so on; and Y designates a hydrogen atom, a halogen atom, nitro group or the like).