A method and system for real-time, computer-generated modifications to an online advertising program is disclosed. One aspect of the invention involves a method at a computer associated with an ad placement provider. The method involves receiving a plurality of data streams containing real-time data concerning online advertisements in an online advertising program for an advertiser; applying a first continuous query to the plurality of data streams; generating a first ongoing response to the first continuous query; applying a second continuous query to the first ongoing response; generating a second response to the second continuous query; and in response to an event associated with generating the first or second response, implementing a computer-generated change in the advertising program in real time.