Nanostructures configured to enhance the intensity of Raman scattered radiation scattered by an analyte include a substantially planar substrate, a plurality of nanoparticles disposed on a surface of the substrate, and a Raman-enhancing material disposed on at least a portion of at least one nanoparticle. Each nanoparticle is configured to emit lased radiation upon stimulation of the nanoparticle and may comprise a nanowire laser. Raman spectroscopy systems include a radiation source, a radiation detector configured to detect Raman scattered radiation scattered by an analyte, a nanostructure including at least one nanoparticle configured to emit lased radiation upon stimulation, and means for stimulating the nanoparticle. Methods for performing Raman spectroscopy include providing a nanostructure including at least one nanoparticle configured to emit lased radiation upon stimulation of the nanoparticle, providing an analyte proximate to the nanoparticle, stimulating the nanoparticle, and detecting Raman scattered radiation.