Use of compounds of general formula (A) as medicaments is described, in particular for the treatment of pain or inflammation; wherein: (I) when X=OH, R.sub.2=NH.sub.2, R.sub.5=CH.sub.2OH, R.sub.6=H, R.sub.1 is C.sub.5-C.sub.6 alkoxy, OCH.sub.2Cyclopropyl, O-(2,2,3,3-tetrafluoro-cycloButyl), phenoxy, substituted phenoxy, OCH.sub.2CH.sub.2OH, or OCH.sub.2CHF.sub.2, (5-indanyl)oxy, C.sub.1, C.sub.2, C.sub.5, or C.sub.6 alkylamino, (R) or (S)-sec-Butylamino, C.sub.5 or C.sub.6 cycloalkylamino, exo-norbornane amino, (N-methyl, N-isoamylamino), phenylamino, phenylamino with either methoxy or fluoro substituents, a C.sub.2 sulfone group, a C.sub.2 alkyl group, a cyano group, a CONH.sub.2 group, or 3,5-dimethylphenyl; or when X=H, R.sub.2=NH.sub.2, R.sub.5=CH.sub.2OH, R.sub.6=H, R.sub.1 is n-hexyloxy; or (II) when X=OH, R.sub.1=H, R.sub.5=CH.sub.2OH, R.sub.6=H, R.sub.2 is NMe.sub.2, N-(2-isopentenyl), piperazinyl, (N-Me, N-benzyl), (N-Me, N--CH.sub.2Ph(3-Br)), (N-Me, N--CH.sub.2Ph(3-CF.sub.3)), or (N-Me, N-(2-methoxyethyl)), or OCH.sub.2Cyclopentyl; or (III) when X=OH, R.sub.5=CONHR.sub.3, R.sub.6=H: R.sub.1 is H, R.sub.3 is an isopropyl group, and R.sub.2 is either NH.sub.2 or a methylamino group (NHMe) or an isoamyl group (CH.sub.2CH.sub.2CHMe.sub.2); or R.sub.1 is H, R.sub.3 is H, and R.sub.2 is NH.sub.2; or R.sub.1 is OMe, R.sub.3 is Ph, and R.sub.2 is NH.sub.2; or R.sub.1 is NHCH.sub.2CH.sub.2CH.sub.2CH.sub.2CH.sub.2Me, R.sub.3 is CH.sub.2CH.sub.2CH.sub.2Me, and R.sub.2 is NH.sub.2; or (IV) when X=OH, R.sub.1=H, R.sub.2=NH.sub.2, R.sub.5=CH.sub.2NHCOR.sub.4, R.sub.6=H, R.sub.1 is n-propyl or NHCH.sub.2CH.sub.3; or (V) when X=OH, R.sub.5=CH.sub.2OH, R.sub.6=H: R.sub.1 is NHCyclohexyl when R.sub.2 is NMe.sub.2; or R.sub.1 is OMe when R.sub.2 is NHBenzyl; or (VI) when X=OH, R.sub.2=NH.sub.2, R.sub.5=CH.sub.2OH, R.sub.6=Me, R1 is NHCyclohexyl or NHCyclopentyl.