The present invention provides an adenovirus serotype 30 (Ad30) fiber
amino acid sequence. The present invention also provides polynucleotides
and expression vectors encoding an Ad30 fiber and viral particles and
cells containing such expression vectors. The present invention further
provides methods of treating genetic diseases or cancers in a mammal
using the polynucleotides, polypeptides, expression vectors, viral
particles and cells of the present invention.