A method of culturing a pearl using a mollusk having mantle tissue that includes placing a first portion of a nucleus adjacent to the mantle tissue and allowing the mollusk to deposit nacre on this first portion of the nucleus; and repositioning the nucleus so a second portion of the nucleus is adjacent to the mantle tissue and allowing the mollusk to deposit nacre on this second portion of the nucleus. Also a cultured pearl produced by a method of placing a first portion of a nucleus adjacent to a mollusk's mantle tissue and allowing the mollusk to deposit nacre on this first portion of the nucleus; and repositioning the nucleus so a second portion of the nucleus is adjacent to the mantle tissue and allowing the mollusk to deposit nacre on this second portion of the nucleus. Further, a method of cultivating a pearl using one or more mollusks each having mantle tissue that includes placing a nucleus adjacent to the mantle tissue of one of the mollusks and sequentially reorienting the nucleus with respect to the mantle tissue of either this mollusk or one or more other mollusks.