The invention provides a cell/tissue culture apparatus capable of applying an optional physical stimulation to a material to be cultivated serving as a cell or tissue to be cultivated and of protecting the material to be cultivated from contamination of various bacteria and so forth. The cell/tissue culture apparatus comprises a chamber (culture chamber 8) for accommodating the material to be cultivated (matrix 10) therein and receiving a culture fluid (18), a disc (24) rotatably installed in the chamber for applying a physical stimulation to the material to be cultivated by way of the culture fluid (18) when it is rotated, and rotary driving means (external rotation body 32 and motor 40) for applying a rotating force to the disc from an outside of the chamber in a state where it does not contact the disc, and it can apply an optional physical stimulation to the material to be cultivated serving as the cell or tissue to be cultivated, protecting the material to be cultivated from contamination of bacteria and so forth.