Pyrrole compounds of Formula (I): and pharmaceutically acceptable salts thereof (where A, B, R.sup.11, R.sup.12, R.sup.13, W, X, Y and Z are as defined herein), which are substituted directly, or by a bridge, with i) a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl and ii) another heteroaryl or aryl ring, with at least one of the rings being further substituted with another ring, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, panic, and bipolar disorder, as well as in the treatment of pain, Parkinson's disease, cognitive dysfunction, epilepsy, circadian rhythm disorders, drug addiction, drug abuse, drug withdrawal, obesity and other diseases ##STR00001##

 
Web www.patentalert.com

< Triamide-substituted heterobicyclic compounds

> Compositions and methods for regulated protein expression in gut

~ 00444