The invention provides bispecific antibodies with selective cytotoxicity against malignant B-cells. The bispecific antibodies bind to an effector cell antigen and to a 28/32 kDa heterodimeric protein on the surface of malignant B-cells. The invention also includes the monospecific components of the bispecific antibodies, humanized versions thereof, and humanized bispecific antibodies. The invention further provides therapeutic and diagnostic methods employing these antibodies.

 
Web www.patentalert.com

< Human antibodies that specifically recognize the toxin Cn2 from Centruroides noxius scorpion venom

> Compositions comprising mixtures of positional PEG isomers of PEGylated G-CSF

~ 00437