An using composition containing cAMP (Cyclic Adenosine Monophosphate), Nicotinic Acid, Prostaglandin, Gamma Linolenic Acid as effective ingredient in management of weight reduction or hypertriglyceridemia, furthermore disclose of certain natural products are essentially contain of said ingredients are to be used for such purpose. For incidence, coffee is the source of caffeine, tea is the source of theophylline, and cocoa is the source of theobromine. Zizyphus jujube mill contains rich amount of cAMP, Radix Angelica Sinensis, Sunflower, Matrimony vine (Lycium chinense Mill), Edible fig (Ficus carica) are sources of Nicotinic Acid, Evening primrose, Starflower contain Gamma Linolenic Acid which are indirect sources of Prostaglandin. This invention discloses the random combination use of the above composition is useful and effective in the management of weight reduction or reducing elevated triglyceride.