A method of making a toy ball having a toy figurine fixed therein includes the steps of: preparing an upper mold and a lower mold; preparing a toy figurine; inserting and fixing the toy figurine to an iron needle of the lower mold; injecting liquid polyurethane glue into the upper mold, combing the lower mold with the upper mold, and turning the combined mold upside down; placing the combined mold on a rotational molding machine for spin-molding the polyurethane glue; cooling the liquid polyurethane glue, and then opening the upper mold and taking out the toy ball from the lower mold; injecting liquid doping with glitter powder or fluorescent powder into the toy ball; sealing a through hole of the toy ball using a plastic sealing needle and then cutting a part of the plastic sealing needle that remains outside the toy ball.