Methods, apparati, and computer-readable media for countering malicious code infections to computer files (20). A preferred embodiment comprises selecting (40) an invariant section of each file (20), wherein said invariant section is invariant to malicious code infections and to repair thereof; for each of a set of known malicious code files, using an algorithm to generate (41) a template corresponding to the invariant section; using said algorithm to define a target (29), corresponding to said invariant section, within a test file (20); comparing (46) the target (29) with the templates; and declaring (48) the presence of malicious code in the test file (20) when the target (29) matches a template.