A radish cultivar, designated ADS-10, is disclosed. The invention relates to the seeds of radish cultivar ADS-10, to the plants of radish cultivar ADS-10 and to methods for producing a radish plant by crossing radish cultivar ADS-10 with itself or another radish cultivar. The invention further relates to methods for producing a radish plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other radish cultivars derived from radish cultivar ADS-10.