Antitumor agents with high antitumor effect have much side-effect, and its
activity decreases when the toxicity decreases. Thus, satisfactory
antitumor effects are not always obtained. Therefore, development of an
antitumor agent having a high antitumor effect, with less side-effect and
low toxicity is awaited. The present invention is to provide an antitumor
agent of fine particles, wherein platinum chloride, chloroplatinic acids
and hydroxyapatite are blend. Platinum chloride and chloroplatinic acids
are platinum tetrachloride, tetrachloroplatinate, hexachloroplatinate,
disodium platinum tetrachloride, disodium platinum hexachloride,
dipotassium platinum tetrachloride, or dipotassium platinum hexachloride.
The maximum particle diameter of hydroxyapatite is 1 .mu.m or less.