The present invention provides novel polynucleotides encoding LTRPC3g,
LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments
and homologues thereof Also provided are vectors, host cells, antibodies,
and recombinant and synthetic methods for producing said polypeptides.
The invention further relates to diagnostic and therapeutic methods for
applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or
LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of
various diseases and/or disorders related to these polypeptides. The
invention further relates to screening methods for identifying agonists
and antagonists of the polynucleotides and polypeptides of the present
invention.