Genes up-regulated in hepatocellular carcinomas and polypeptides encoded
by these genes are provided. Vectors, transformants and methods for
producing the recombinant polypeptides are also provided. Probes and
primers of these genes and antibodies against the polypeptides are also
provided. The probes, primers and antibodies can be used as reagents for
detecting hepatocellular carcinomas. Methods for detecting hepatocellular
carcinomas using such detection reagents are further provided. Antisense
nucleolide sequences of these genes are also provided and can be used to
inhibit growth of hepatocellular carcinomas.