This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the --OH group at the 3'-position of the deoxyribose.

 
Web www.patentalert.com

< Fluorescent protein and chromoprotein

> Aequorin and obelin mutants with differing wavelengths and bioluminescence

~ 00418