The present invention concerns a multi-layered cell, particular a liquid crystal display cell (1), or an electrochemical photovoltaic cell, or a combination of a liquid crystal display cell and an electrochemical photovoltaic cell, this multi-layered cell comprising n superposed substrates (2, 4, 6, 8), n being an integer number greater than or equal to three, these substrates (2, 4, 6, 8) being joined by sealing frames (14, 16, 18) delimiting (n-1) sealed cavities (20, 22, 24) for containing an optically or electro-optically active medium, the upper surface (10) of the first substrate (2) and the lower surface (12) of the last substrate (8) forming the external faces of the cell (1), said multi-layered cell (1) being characterised in that it includes (n-1) filling holes (26, 28, 30) arranged, at least in part, on one side or other of the cell (1), said (n-1) filling holes (26, 28, 30) each communicating with a different cavity and passing through at least one cavity to reach the cavity with which they are connected, said (n-1) filling holes (26, 28, 30) being isolated from the cavity or cavities through which they pass.