A tire pressure sensor assembly is provided for use with a wheel rim including a valve hole. The sensor assembly including a metal valve stem element having a stem base, a stem body, a stem cap end, and an inner stem chamber. A lower sensor housing is rigidly over-molded onto the stem base and forms a sensor storage chamber. A tire pressure sensor element is mounted therein. An outer rubber seal is over-molded onto the stem body and includes an inner retention portion, an outer retention portion, and a retention groove configured to allow the metal valve stem element to be press-fit and retained into the valve hole. A plurality of vent holes are formed spaced around an outer perimeter of the stem base to allow universal orientation within the valve hole.