The present invention is directed to compounds of formula I which are
inhibitors of the beta-secretase enzyme and that are useful in the
treatment or prevention of diseases in which the beta-secretase enzyme is
involved, such as Alzheimer's disease. The invention is also directed to
pharmaceutical compositions comprising these compounds and the use of
these compounds and compositions in the prevention or treatment of such
diseases in which the beta-secretase enzyme is involved ##STR00001##