Composition of matter for application to a body surface or membrane to
administer warfarin by permeation through the body surface or membrane,
the composition comprising warfarin to be administered, at a
therapeutically effective rate, alone or in combination with a permeation
enhancer or mixture. Also disclosed are drug delivery devices containing
the warfarin or warfarin and enhancer composition and methods for the
transdermal administration of the warfarin and warfarin/enhancer
composition.