There is provided a method of designing a probe from a polynucleotide
group comprising a plurality of polynucleotides, the method including:
forming a polynucleotide group by selecting polynucleotides having a
certain sequence; producing polynucleotide fragments having a certain
length from each of the polynucleotides of the polynucleotide group and
obtaining sequence and position information on the polynucleotide
fragments; providing each polynucleotide fragment with a sequence
specific identification number using the obtained sequence and position
information of the polynucleotide fragments; and comparing the
identification numbers of the fragments to select the probe.