The present invention provides devices for closing septal defects, such as
a patent foramen ovale (PFO). The closure devices include a proximal
anchor member, a distal anchor member, and at least one flexible center
joint connecting the two anchor members. According to some embodiments,
the proximal and/or distal anchor members may include a generally
cylindrical member split along the central portion of its length to form
an elongate oval. The proximal and/or distal anchor members may further
include a tissue scaffold. At least some of the closure devices according
to the present invention are repositionable and retrievable.