A method and mobile station (MS) for synchronizing radio signal transmission times in a radiotelephone network. The MS measures a frame reception time for an nth frame, and obtains information regarding an offset between the times of transmission and reception of the nth frame. The MS then calculates a transmission time at the mobile station for the nth data frame using the timing offset information and the measured frame reception time. For a later mth frame, if new timing offset information has been received, the MS calculates a transmission time for the mth frame using the new information and the measured reception time for the mth frame. If new information has not been received, the MS calculates the transmission time based on the difference between the reception times of the nth and mth frames, the number of frames between the nth and mth frames, and the timing offset information obtained at the nth frame.