Milling procedure performed on the patient's bone or other tissue in order to form in said tissue a cavity of a shape and size that allows it to house an implant (or for other purposes where the tissue must regenerate) wherein milling is performed at low speeds and without irrigation without the tissue heating up and necrosis occurring in the tissue. The special design of the mill tools enables the tissue particles extracted during the milling process to be collected without using a suction machine. Said particles are in optimal biological condition for use in autografting due to the fact that neither overheating nor irrigation occur during the milling process.