Imaging, testing and/or analysis of subjects is facilitated with a micro-mirror-based access approach. According to an example embodiment, a micro-mirror is implemented to direct light to a live being such as a biological specimen or a living being. Light from the live being is detected and implemented for use in analyzing the live being. In certain applications, the micro-mirror is fastened to a live being, such as to a skull of a live mouse, while the live being is allowed to move in an unanesthetized state. Behavior of the live being and detected response from the live being are concurrently used to analyze the live being.