The invention relates to a treatment composition for exfoliating skin comprising a particulate erasing agent, the particles of the erasing agent being dimensioned to roll along a surface. The particles have an average maximum diameter of between 30 and 1000 microns and consist of a precipitate of calcium carbonate. A method of skin exfoliation which employs the treatment composition of the invention is also disclosed.

 
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> Diagnostics and therapeutics for diseases associated with phosphodiesterase 1a (pde1a)

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