A method for treating stenosis in a spine of a patient having a median plane, wherein the spine includes a spinal canal having a posterior surface, a dural sac and an epidural space between the posterior surface and dural sac, the location of the stenosis determining a region of interest in the spine. In an embodiment the method comprises the steps of a) generating at least one view of a portion of the spinal canal in the region of interest; b) compressing the dural sac in the region of interest by injecting a fluid to form a safety zone and establish a working zone in the region of interest, the safety zone lying between the working zone and the dural sac; c) percutaneously accessing the epidural space in the region of interest on a first side of the median plane; d) inserting a tissue removal tool into tissue in the working zone on the first side of the median plane; e) using the tissue removal tool to percutaneously reduce the stenosis on the first side of the median plane; and f utilizing the at least one view to position the tissue removal too during at least a part of step d) and at least part of step e)