Integrin receptor antagonists whose molecular structure includes a tetrahydropyridimidinylaminoethyloxybenzoyl group on a sulfonylamino-.beta.-alanine nucleus exhibit increased binding affinity for the .alpha.v.beta.3 receptor when further substituted on the sulfonyl moiety with an N-amino alkycarbamyl group or a butyloxycarbonylamino alkylcarbamoyl group or similar groups.

 
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> Hydrogels formed by non-covalent linkages

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