The present invention refers to a formulation for a slimming treatment comprising in certain quantities: hypothalamus powder, hypophysis powder, thyroid powder, suprarenal cortex powder and pancreas powder, and other polyglandular opotherapic extracts such as extract of ovary or testicle; said slimming treatment being evaluated and optimised thanks to an exponential mathematical model which models the accumulated weight loss of a patient by means of a differentiation and separation of the slimming effect due to the set of factors depending on the applied slimming treatment and, on the other hand, of the slimming effect due to the set of factors depending on the typology of the patient trying to slim.