An RF transceiver for coupling an RF signal through a target area, having a transmission head having a transmission inductor having a first axis directed toward a target area, an RF generator capable of generating a hyperthermia-inducing RF signal having at least one component for transmission via the transmission head, the RF signal being capable of heating at least one of target cells and RF absorption enhancers associated with target cells to thermally damage the target cells, a reception head for receiving the RF signal and having a reception inductor having a second axis directed toward the target area, a first tuned circuit in circuit communication between the RF generator and the transmission head, and a second tuned circuit in circuit communication between the reception head and a load, and wherein the first and second tuned circuits cooperate with each other and the transmission and reception heads to form a high-Q circuit for coupling the RF signal through the target area. The tuned networks may be simple or elaborate pi-networks and may have tunable components to help couple a desired amount of power from the transmission head to the reception head through the target area.