An inhaler device comprises an inhaler body defining a recess for a capsule holding herein a substance to be inhaled, and a nosepiece communicating with the capsule, and a perforating element coupled to the inhaler body and provided for perforating the capsule for allowing an outside air flow to be mixed with the capsule contents and inhaled through the nosepiece.

 
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> Breathing circuits having unconventional respiratory conduits and systems and methods for optimizing utilization of fresh gases

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