Cleansing wipes comprising a film forming polymeric material and a cleansing agent stored in dry form are disclosed. The cleansing wipes are water disintegratable such that upon contact with water, the cleansing wipes release the cleansing agent and begin to dissolve/disperse into the water. Full dissolution/dispersion of the cleansing wipes occurs in about 60 seconds or less after contact with water to allow for a sufficient time for cleansing of the hands or other skin area.