The present invention provides a three-piece solid golf ball having excellent shot feel, controllability, rebound characteristics, scuff resistance, yellowing resistance and productivity. The present invention relates to a three-piece solid golf ball comprising a core composed of a center and an intermediate layer formed on the center, and a cover formed on the core, wherein the cover comprises a mixture of polyurethane-based thermoplastic elastomer and polyamide-based thermoplastic elastomer as a base resin.