A novel soybean cultivar, designated SN64195, is disclosed. The invention relates to the seeds of soybean cultivar SN64195, to the plants of soybean SN64195 and to methods for producing a soybean plant produced by crossing the cultivar SN64195 with itself or another soybean variety. The invention further relates to hybrid soybean seeds and plants produced by crossing the cultivar SN64195 with another soybean cultivar.