Method and apparatus to predict the onset of earthquakes, one to three days prior to the event. Predictions of latitude, longitude, and time of occurrence of an incipient earthquake, by monitoring and exploiting unique changes in the ionosphere and atmosphere, may be obtained. The methodology, focused on radio-tomography of the ionosphere, includes data receiving, transmission, and analysis stations on the earth's surface; data from satellite transmitters; and mechanisms to extract earthquake-related signatures that are correlated, processed, interpreted, and disseminated as warnings from central analysis centers. Additionally, data from ground-based radars that display unique clutter maps during earthquake pre-cursor activity and data from cellular telephone networks that display signal fading may also be used.