The invention provides for compounds of formula I ##STR00001## wherein the substitutents are as described herein.Further provided are methods of using such compounds for the treatment of eating disorders, metabolic disorders, obesity, cognitive disorders, neurological disorders, pain disorders, inflammation disorders, in the promotion of smoking cessation and for the treatment of other psychiatric disorders Also provided are pharmaceutical compositions containing such compounds and pharmaceutical combinations of the compounds of the invention with other therapeutic agents.

 
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> Genetic polymorphisms associated with coronary stenosis, methods of detection and uses thereof

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